Dr Phyllis Mullenix – Pharmacologist and Toxicologist

Dr. Phyllis Mullenix on the Neurotoxicity of Fluoride

DR. PHYLLIS J. MULLENIX, Ph.D. is a pharmacologist and toxicologist by training… In the 1980s, Dr. Mullenix was Head of the Toxicology Department at the Forsyth Dental Center, a world renowned dental research institution affiliated with the Harvard Medical School. She was invited to start Forsyth’s Toxicology Department because of her expertise in neurotoxicology. She is presently a Research Associate in Psychiatry at the Children’s Hospital Medical Center in Boston. Dr. Mullenix’s academic appointments, professional positions held, teaching experience, awards, honors and many published scientific research articles to her name are numerous.

The first test Dr. Mullenix was asked to perform at the Forsyth Dental Center was a test related to neurotoxicity of fluoride. The person who asked her to perform this test was Dr. Harold C. Hodge, one of the founders of the Society of Toxicology. Since that time, Dr. Mullenix has conducted additional research related to fluoride including one study, which is about to be published. She is considered one of the foremost experts on the neurotoxicity of fluoride compounds..

Documentary, Dr. Phyllis Mullenix Fluoride Forum Clark University Worchester, MA October 24, 1996 Why haven’t they taken fluoride off the market? Evidence shows that it is a toxic poison. …POISON





Dr. Mullenix gives an excellent description to the IAOMT of exactly how the fluoride ion interacts with human physiology to cause numerous adverse health effects. She describes in some detail its effects on various organ systems in clouding the issues her research into neurological impairment especially during pregnancy raised in 1995. Many dental offices apply topical fluoride during pregnancy. This would appear to be very unwise considering the fact that Dr. Mullenix used exactly the same level of blood fluoride in her experiment as a child will experience from this procedure.




Mullenix is also one more casualty of the fluoride wars. She had nothing to do with the fluoride issue originally, but became involved as part of herwork. All she “knew” about fluoride when she started was that it was supposedly good for your teeth. She was not excited about performing theresearch, but was doing it because she was asked. Her research results were published in Neurotoxicology and Teratology (Vol.17, No. 2, pp.169-177,1995), the leading scientific journal in the field. Before that paper was published, she presented her findings at the National Institute of DentalResearch (NIDR) in Maryland, a division of the National Institute of Health (NIH). When she arrived at the NIDR, in her words, “I had no idea what I was getting into. I walked into the main corridors there and all over the walls was ‘The Miracle of Fluoride’. That was my first real kick-in-the-pants as to what was actually going on.” She said that the display ridiculed the people against fluoridation. “I thought, ‘Oh great!’ Here’s the main NIH hospital talking about the ‘Miracle of Fluoride’ and I’m giving a seminar to the NIDR telling them that fluoride is neurotoxic!”[48] After her presentation to the NIDR, she met with toothpaste representatives who asked her if she was saying that their products lowered the IQs of children, and Mullenix responded, “basically, yes.” That marked the end of her career.

When she excitedly announced to her employers that her paper on the

intelligence of rats was being published, three days later she was fired.

Right after she was fired, her former employers asked her which journal was

going to publish her work. By that time, she realized that they wanted to

block its publication, so she did not tell them. Subsequently, funding has

dried up for that kind of research, though immediately after Mullenix was

fired, Colgate gave a $250,000 grant to Forsyth (for a job well done?). The

unique equipment Mullenix developed to test rat intelligence was mysteriously

destroyed before she could recover it.

Dr. Mullenix was then given an unfunded research position at Children’s

Hospital in Boston, but with no equipment or money. Mullenix said, “The

people at Children’s Hospital, for heaven’s sake, came right out and said

they were scared because they knew how important the fluoride issue was…Even

at Forsyth they told me I was endangering funds for the institution if I

published that information.”[49]

Mullenix has since applied to the NIH for a research grant to further her

research, and was turned down. The NIH told her that fluoride had no central

nervous system effects, period. How the NIH concluded that, when about the

only published research shows deleterious effects, is curious indeed. The

work Mullenix did, as well as other recent studies[50], has shown that the

fluoride ion is particularly damaging to the brain’s hippocampal region,

which is its learning center.

Mullenix’ fate is common, and my work documents many instances of scientists

and others arriving at the “wrong” answers, and having their careers

destroyed. Other scientists who had their careers ruined for coming up with

the “wrong” answer regarding fluoridation include Dr. Allan S. Gray of

British Columbia and Dr. John Colquhon of Auckland, New Zealand.

In light of Hodge’s secret work for the Manhattan Project, and the secret

memos and secret studies that are the tip of the iceberg, every

pro-fluoridation effort that uses Hodge’s name is tainted. It was with

interest that I read Fluoride and Dental Caries. It is a recent book on the

subject, published in 1986. The book is a compendium on fluoridation,

drawing on various experts in the field. Hodge co-wrote a chapter on

fluoride toxicity, and he wrote a chapter dealing with objections to

fluoridation. Reading that book was another enlightening process, when I got

over my anger. The book gives the appearance of looking at fluoridation from

many aspects, but appearance is the operative word. Hodge’s work we already

know is suspect, to put it mildly, and I looked there first.

Hodge’s co-author on the toxicology chapter was another fluoridation

luminary: Frank Smith from the University of Rochester. With that

professional pedigree and affiliation with Hodge, it is nearly certain that

Smith was also deeply involved with the Manhattan Project. I take it for

granted that with that background, I can trust nothing they write. It is

instructive to see the blind spots in their work, and what they are obviously

hiding. When Smith and Hodge stated that “No substantive evidence of ill

health has ever been offered in children or adults as a result of consuming

drinking water containing optimal concentrations of fluoride,”[51] they are

voicing the nuclear establishment’s damage control opinion, because there is

substantial evidence of harm, but they chose to ignore it. When they say,

“Since the Danish experience (in the 1930s) crippling fluorosis in an

industrial setting has never been seen in the United States or Europe,”[52]

take a grain of salt with that statement. With just one declassified study,

out of many that exist and are still secret, definite harm occurred, though

by playing semantics games we could say they were not “crippled,” just

toothless, though the long-term effects are unknown, which might be in

another classified study. People getting violently ill from du Pont’s

fluoride cloud is another invisible event, at least to the public, when Hodge

and Smith wrote their masterpiece of disinformation. The worst air pollution

disaster in U.S. history happened in October 1948 in Donora, Pennsylvania,

when an air inversion layer formed over the town for four days, and fluoride

emissions from U.S. Steel’s zinc and steel facilities killed twenty people

and seriously injured hundreds more. If the inversion layer had lasted one

more day, a thousand people may have died. U.S. Steel and the PHS conspired

to cover-up the disaster, with records missing to this day.[53]

Throughout Fluoride and Dental Caries, there were instances of “looking” at

objections to fluoridation, and the appearance of looking at them was

undertaken. The close relationship between ALCOA, the other fluoride

polluters and the early fluoridation researchers is nowhere mentioned,

although it is well documented and is consistently one of the biggest issues

raised by fluoridation’s opponents. A table on the “anti-science” arguments

against fluoridation was even produced on page 130, in a chapter titled

“Legal, Social and Economics Aspects of Fluoridation,” that even mentioned

the “Communist conspiracy” aspect of fluoridation. Nowhere was mentioned

the obvious economic incentives of fluoride polluters to manage the

fluoridation issue, and the well-documented instances of them funding and

influencing the fluoridation research, even when it is merely the smoking gun

of conflict of interest. The authors of that chapter, including the book’s

editor, trotted out the words “pseudoscientist” and “quack” to describe

fluoridation opponents and their “anti-science.” In the chapter purporting

to look at the broad spectrum of issues regarding fluoridation, the ALCOA and

fluoride polluter issue was spectacularly absent.

In Fluoride and Dental Caries, one area caught my interest. In Hodge’s

chapter on fluoridation objections, he presented experimental evidence by a

group of chemists that showed the fluorine ion benign to human chemistry.

The research was used to discredit John Yiamouyiannis, who uses the very same

research to show how the fluorine ion wreaks havoc in the body. Hodge

interpreted the original research, qualifying and minimizing the conclusions,

and then he presented the experimental work of pro-fluoridation pal

Armstrong. Hodge concluded that the research showed that the fluorine ion

was relatively harmless by itself. That part was interesting, because it is

the first time that I have seen Yiamouyiannis’ science challenged, beyond his

cancer statistic analyses with Dean Burk. With knowing Hodge’s extreme and

formerly secret bias, I cannot trust his writing, particularly regarding the

fluoride ion and human harm, but it was interesting reading. When anybody is

proven a systematic liar, can you believe anything they say? How do you

separate fact from fiction in those cases? The only way I know is to

entirely reject their work and become your own expert.

Here are some quotes regarding the biological damage the fluorine ion does to

human health, the kind you will not find in pro-fluoridation propaganda like

Fluoride and Dental Caries. Yiamouyiannis’ contentions are herein supported.



“Fluorides are general protoplasmic poisons, probably because of their

capacity to modify the metabolism of cells by changing the permeability of

the cell membrane and by inhibiting certain enzyme systems. The exact

mechanism of such actions is obscure.” – Journal of the American Medical

Association, Sept 18, 1943. (before the propaganda steamroller really got

going in 1947)

“The fluoride ion exerts its toxic effect by inhibiting the action of many

enzyme systems.” – Hugo Theorell, M.D., Nobel Prize winner for his research

in the field of enzyme chemistry.

“We ought to go slowly. Everybody knows that fluorine and fluorides are very

poisonous substances and we use them in enzyme chemistry to poison enzymes,

those vital agents in the body. That is the reason things are poisoned;

because enzymes are poisoned, and that is why animals and plants die.” –

James B. Sumner, Director of Enzyme Chemistry, Department of Biochemistry and

Nutrition, Cornell University, and a Nobel Prize winner for his work in the

field of enzyme chemistry.

“The data indicated that drinking water with as little as 1 PPM shortened the

life span of mice an average of nine per cent. This was true whether death

was due to cancer or non-cancerous diseases. The only notice proponents of

fluoridation gave to this work was to discredit it as much as possible. …

In experiments where the drug was added directly to suspensions of cancer

tissue before inoculation into eggs or mice, sodium fluoride stimulated the

growth of cancer tissue in concentrations of one part in more than 20

million. Scientists at Cambridge University (British Medical Journal, Oct

26, 1963) discovered that concentrations of sodium fluoride as low as one

part in ten million inhibited the growth of a culture of human tissue. …

the growing weight of scientific evidence that water-borne fluorides, even at

1 PPM, have toxic possibilities must finally be recognized.” – Alfred

Taylor, Ph.D., Clayton Foundation, Biochemical Institute, University of

Texas, Austin Texas, 1965.

“The terrifying conclusion of the studies was that fluorine greatly induced a

cancer tumor’s growth. If doctors and the public can be made aware of this

catastrophe, fluoridation shall end quickly. It will someday be recognized

as the most lethal and stupid “Health Program” ever conceived by the mind of

man, witch doctors and blood-letters not excepted.”

“In 1969 the country of Sweden intended to fluoridate their water supply due

to the strong advice of Professor Yngve Ericsson, a Swedish dentist who was

also the senior representative on the World Health Organization’s Expert

Committee on Fluoridation. However, it was then found that Professor

Ericsson coincidentally was the holder of two highly-profitable patents on

fluoride toothpaste!” – Alfred Taylor, June 13, 1970 the Gothenburg Post

(Sweden); August 5, 1970 the News Register (Sweden); and May 1, 1970 Norsk

Folkehelselag (Norway).

“In 1978, the West German Association of Water and Gas Experts rejected

fluoridation for legal reasons, and because ‘the so-called optimal fluoride

concentration of 1mg/liter is close to the dose at which long-term damage to

the human body is to be expected.’” – Chemical and Engineering News, August

1, 1988.


All in all, the tremendous blind spots regarding fluoride polluters, diet and

caries, the severe biases regarding the harm done by fluorides, and Hodge’s

secret mission on behalf of the nuclear establishment rendered Fluoride and

Dental Caries virtually worthless, except as an instructive exercise in

propaganda. With the now-known nuclear industry’s very active though secret

management of the fluoridation issue, books like Fluoride and Dental Caries

are examples of “pseudoscience” in the strongest sense.

The situation of industry and government corrupting science is far from

confined to the fluoridation issue. Today, ethyl alcohol, the substance that

every drunkard knows well, is added to American gasoline to increase its

octane rating. It works great. It was also used eighty years ago. In the

1920s, ethyl alcohol was replaced by tetraethyl lead as an octane booster.

Why? As it turns out, nobody could patent ethyl alcohol and make big

monopoly profits from putting it into gasoline. Therefore, General Motors,

Standard Oil and du Pont conspired to make a new, patentable chemical, and

tetraethyl lead was introduced into American gas tanks. Even though even Ben

Franklin remarked on lead’s well-known toxic qualities hundreds of years ago,

and even ancient Romans and Greeks wrote of its toxic properties,

industrially-funded scientists in the 20th century labored mightily to make

lead appear safe to ingest, even though they knew how deadly tetraethyl lead

really was. It is unknown just how many people got sick and died from the

effects of lead being spewed into the air during the era of tetraethyl lead,

but it is certainly not inconsiderable. In 1985, the EPA estimated 5,000

lead-related heart disease deaths per year, prior to the tetraethyl lead

phase out. The lead content of American bloodstreams has fallen

precipitously since tetraethyl lead was outlawed. The most notorious of the

industrial laboratories that produced the lead “research” was Kettering

Laboratories.[54] For generations, Kettering and its industrial sponsors

controlled all the lead research. The “Kettering” of Kettering Laboratories

was Charles Kettering, the inventor and General Motors executive. Kettering

Laboratories is not the only “medical” foundation that he helped bankroll.

The Memorial Sloan-Kettering Cancer Center, the leading cancer research

institute in the world, is named after Kettering and his buddy, General

Motors CEO Alfred Sloan, another noted “philanthropist.” Kettering

Laboratories also was instrumental in making aluminum appear to be a benign

substance, and Kettering’s efforts on the fluoridation issue are well known.

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