CTD is a robust, publicly available database that aims to advance understanding about how environmental exposures affect human health. It provides manually curated information about chemical–gene/protein interactions, chemical–disease and gene–disease relationships. These data are integrated with functional and pathway data to aid in development of hypotheses about the mechanisms underlying environmentally influenced diseases.
DiseasesCTD’s MEDIC disease vocabulary is a modified subset of descriptors from the “Diseases” category of the U.S. National Library of Medicine (NLM) Medical Subject Headings (MeSH®), combined with genetic disorders from the Online Mendelian Inheritance in Man® (OMIM®) database. CTD biocurators mapped OMIM diseases to terms within the hierarchical MeSH disease vocabulary to expand our disease representation. This combined vocabulary is used to curate gene–disease and chemical–disease associations. You can browse diseases, or use them to formulate gene or reference queries.